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Updated: Jun 23, 2025

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
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托利德通过调节TET2介导的ZO-1氧甲基化来降低细胞的透性

Yue-Wen Tang1,2, Meng-Ya Jiang1, Jia-Wei Cao1

  • 1Department of Nephrology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China.

Experimental biology and medicine (Maywood, N.J.)
|June 17, 2024
PubMed
概括

托利德 (TP) 通过上调TET2的调节,增加Zonula occludens 1 (ZO-1) 在细胞损伤模型中的表达,从而降低透性. 这种表观遗传调节为蛋白尿症提供了潜在的治疗策略.

关键词:
在TET2的基础上.三托利化物是什么ZO-1 是一个ZO-1氧甲基化氧甲基化波多细胞的透性

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