低剂量计算机断层扫描和活检用于评估高风险人群中的肺癌患病率和相关因素
Duy Hoang Tran1,2, Tho Van Nguyen2,3, Linh Thi My Luong1
1Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, 90000, Viet Nam.
Heliyon
|June 17, 2024
概括
肺癌是全球主要的死亡原因之一. 在越南,一项研究发现,吸烟超过30包年和慢性阻塞性肺病 (COPD) 显著增加了通过低剂量CT扫描在高风险个体肺癌检测的风险.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 肺部病理学 肺部病理学
背景情况:
- 肺癌是第二个被诊断为癌症的癌症,也是全球癌症死亡的主要原因.
- 很少有研究使用低剂量CT扫描来评估肺癌患病率和风险因素.
- 越南面临着肺癌的重大负担,需要研究早期检测方法.
研究的目的:
- 为了确定高风险越南人群中肺癌的患病率.
- 通过低剂量CT扫描检测出与肺癌相关的因素.
- 评估低剂量CT查在这个人口群体中的有用性.
主要方法:
- 越南169名高风险患者的横截面分析.
- 患者接受了体检和低剂量CT扫描.
- 对CT识别的异常进行了活检;用于评估风险因素,使用了单变量和多变量分析.
主要成果:
- 在169名患者中,肺癌的患病率为2.37%,为4例.
- 肺癌病例包括腺癌和状细胞癌.
- 吸烟 (≥30包年) 和慢性阻塞性肺部疾病 (COPD) 与CT扫描异常风险增加有显著关联 (p <0.05).
结论:
- 在研究的越南高风险人口中,肺癌的患病率显著.
- 吸烟史和COPD是CT扫描异常的重要风险因素,表明潜在的肺癌风险.
- 低剂量CT查可能对识别高风险越南人的肺癌有价值.
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