系统性审查和剂量分析:高压氧疗法在治疗创伤后应激障碍中的有效性
Susan R Andrews1, Paul G Harch2
1Neuropsychological Services for Children and Adults, Metairie, LA, United States.
Frontiers in neurology
|June 17, 2024
概括
高压氧疗法 (HBOT) 显示了创伤后应激障碍 (PTSD) 的显著症状改善. 较高的HBOT剂量可能会导致可逆的情绪症状恶化,但总的来说,它为PTSD提供了有希望的治疗方法.
科学领域:
- 神经科学是一个神经科学.
- 高压医学的高压医学.
- 精神病学是一个精神病学.
背景情况:
- 研究表明,高压氧疗法 (HBOT) 通过改善PTSD症状,可以有效治疗创伤后应激障碍 (PTSD).
- 这次系统性审查和剂量分析调查了患有PTSD症状的患者的HBOT.
研究的目的:
- 系统地审查和分析用于治疗PTSD症状的HBOT剂量.
- 评估HBOT在患有PTSD的军人和平民群体中的有效性和安全性.
主要方法:
- 在PubMed,CINAHL和Cochrane数据库中搜索了成人英语HBOT和PTSD临床研究.
- 选择随机试验和具有症状结局的研究,根据氧气剂量和氧气压力进行分析.
- 使用国家PTSD指南中心评估结果,并使用PEDro尺度确定方法质量.
主要成果:
- 八项研究 (393名受试者) 显示,在1.3-2.0 ATA的40-60个HBOT疗程后,PTSD症状的统计学上显著改善.
- 观察到线性剂量-反应关系,较高的累积氧气剂量与更大的症状改善相关.
- 严重的,可逆的情绪症状恶化发生在最高剂量的30-39%的受试者中;其他副作用是轻微的和短暂的.
结论:
- 在患有PTSD症状的患者中,HBOT显示出显著的症状改善,可靠的变化或临床显著的变化.
- 在受PTSD影响的区域中,功能和微观结构脑成像变化支持了症状的改善.
- 研究结果表明,PTSD可能具有超出严格精神病学分类的神经生物学基础.
关键词:
在这里,HBOT是HBOT.创伤后应激障碍 (PTSD) 是一种焦虑症 焦虑症 焦虑症高压氧气疗法 (hyperbaric oxygen therapy) 是一种高压氧气疗法.创伤后应激障碍 创伤后应激障碍创伤的创伤创伤的创伤.治疗治疗治疗治疗治疗治疗更多相关视频
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