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在剖腹产后大规模出血的患者中,手术内细胞救援对凝血功能结果的影响

Huabei Zeng^1,2, Chunhua Xia², Zhiyong Cheng²

¹Wuxi Medical College, Jiangnan University Wuxi 214122, Jiangsu, China.

American journal of translational research

|June 17, 2024

概括

与异构输血 (ABT) 相比,手术内细胞救援 (ICS) 改善了凝血并减少了剖腹产后大规模出血 (PCSH) 的不良事件. 早期监测凝血是改善患者治疗结果的关键.

科学领域:

产科和妇科产科和妇科
输血医学输血医学
管理出血管理出血

背景情况:

大规模剖腹产后出血 (PCSH) 对母亲的健康构成重大风险.
有效的管理策略对于改善患者预后和减少并发症至关重要.

研究的目的:

评估手术内细胞挽救 (ICS) 在重建大量PCSH患者的凝血功能方面的疗效.
在这个患者群体中,比较ICS与全基输血 (ABT) 的结果.

主要方法:

对60个严重的PCSH病例进行了回顾性分析.
患者被分为一个ABT组 (n=30) 和一个ICS组 (n=30).
输血前后评估了凝血参数,血液细胞计数和不良反应.

主要成果:

与ABT组相比,ICS组显示凝血功能的恢复明显更快 (减少PT,APTT,TT;增加FIB).
在ICS组中,不良反应的发生率显著降低 (3.33%对23.33%).
低FIB (<1.52 g/L) 和高HR (<45.35次/分钟) 被确定为不利结果的风险因素.

结论:

与ABT相比,ICS在管理大规模PCSH方面具有优势,促进更好的术后恢复和凝血功能.
基于凝血和血液气体分析的早期检测和干预对于优化患者护理和结果至关重要.

关键词:

在手术内进行细胞救援.剖腹产是一个剖腹产.临床结果临床结果凝固的功能是凝固的功能.产后出血产后出血

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