怀孕期间的COVID-19感染和婴儿听力损失:一项临床研究
Rethesh Senthil1, Abirami1, Nikhil Sivanand1
1Department of ENT, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pillaiyarkuppam, Pondicherry India.
概括
这项研究调查了COVID-19的母亲生下的婴儿的听力损失. 发现患病率为0.005,表明母体SARS-CoV-2感染对新生儿听力没有直接影响.
科学领域:
- 新生儿健康新生儿健康
- 传染病流行病学 传染病流行病学
- 听力学 听力学是指听力学.
背景情况:
- 怀孕期间的母体COVID-19感染引发了对新生儿健康潜在影响的担忧.
- 了解SARS-CoV-2对听觉发育的影响对于早期干预至关重要.
研究的目的:
- 为了确定怀孕期间经历了COVID-19感染的母亲出生的新生儿中听力损失的患病率.
- 评估母体SARS-CoV-2感染对新生儿听力的直接影响.
主要方法:
- 一项对1960名新生儿的前性观察性研究,这些新生儿是来自RTPCR确诊的COVID-19阳性母亲.
- 使用耳声发射 (OAE) 的新生儿听力查,重复测试失败.
- 脑干唤起响应听力测量 (BERA) 用于持续OAE失败的新生儿.
主要成果:
- 在1960名新生儿中,380名 (19.9%) 最初没有通过OAE查.
- 经过重复测试和BERA,十名新生儿被诊断患有感觉神经听力损失.
- 在这个队列中,听力损失的总体患病率为0.005.5.
结论:
- 该研究发现,暴露于母体COVID-19的新生儿中,听力损失的患病率较低 (0.005),表明对新生儿听力没有立即的不良影响.
- 建议对更大的队列进行进一步研究和扩展后续调查,以检测潜在的延迟听力影响.
- 发现有听力损失的新生儿需要长期监测对认知和整体健康的潜在影响.
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