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Updated: May 11, 2026

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs

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第3期随机化COMMODORE 2试验:克罗瓦利马布与埃奎利祖马布在患有阳性夜间血红蛋白尿症的患者中,无需补充抑制

Alexander Röth1, Guangsheng He2, Hongyan Tong3

  • 1Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

American journal of hematology
|June 17, 2024
PubMed
概括

克罗瓦利马布在治疗阳性夜间血红蛋白尿症方面表现出与埃库利祖马布的非劣势,在血液溶解控制和输血避免方面表现出相似的疗效. 这种新型的C5补充抑制剂提供了一个方便的自我管理选项,具有类似的安全性.

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