ICA1PICK1-PKCαAPP

Liangye Ji1, ZiJun Meng1, Xiangjun Dong1

  • 1Department of Pediatric Research Institute Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation base of Child development and Critical Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China.

概括

在阿尔茨海默氏病 (AD) 中,岛屿细胞自身抗原1 (ICA1) 的表达减少. ICA1影响了粉样前体蛋白的加工,这表明它是AD的潜在治疗标.

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