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Updated: Jun 23, 2025

Modeling Ovarian Cancer Multicellular Spheroid Behavior in a Dynamic 3D Peritoneal Microdevice
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在高度的血清性卵巢癌中,由内甲素-1驱动的瘤-肌瘤前循环

Piera Tocci1, Celia Roman1, Rosanna Sestito1

  • 1Preclinical Models and New Therapeutic Agents Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Regina Elena National Cancer Institute, Rome, Italy.

Clinical science (London, England : 1979)
|June 17, 2024
PubMed
概括

内甲素-1 (ET-1) 和血管内皮生长因子 (VEGF) 形成关键的前循环 (FFL),驱动高度血清性卵巢癌 (HG-SOC) 转移. 用macitentan阻止这些ET-1/VEGF FFL为HG-SOC提供了一个有前途的治疗策略.

关键词:
结末素-1受体的受体是什么卵巢癌是发生在卵巢的癌症.瘤微环境是一个微环境.

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