系统性偏见促进边缘化群体在随机对照试验中被低纳入同时出现的酒精使用和创伤后应激障碍:一个交叉分析
Mallet R Reid1, Nicole T Buchanan1
1Michigan State University, East Lansing, Michigan.
Journal of ethnicity in substance abuse
|June 17, 2024
概括
彩色人种和白人妇女在临床试验中代表性不足,因为同时发生的创伤后应激障碍和酒精使用障碍. 研究必须解决系统性偏见,以确保所有人群的公平治疗发展.
科学领域:
- 临床心理学 临床心理学
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 同时发生的创伤后应激障碍 (PTSD) 和酒精使用障碍 (AUD) 不成比例地影响有色人种,导致更糟糕的结果.
- 种族和民族少数群体面临着严重的障碍,无法获得有效的,文化上适当的治疗,以治疗PTSD和AUD的同时发生.
- 确保治疗疗效需要在研究中的多样化代表,特别是在随机对照试验 (RCT) 中.
研究的目的:
- 调查RCT中种族和种族群体和性别的纳入,用于同时发生的PTSD和AUD.
- 确定可限制边缘化群体参与的RCT方法论中的潜在偏见.
主要方法:
- 使用统治矩阵框架进行交叉分析.
- 在已发表的RCT中评估了参与者的种族和性别代表性,用于同时发生的PTSD和AUD.
主要成果:
- 有色人种和白人女性在RCT中显著不足,因为PTSD和AUD同时发生.
- 风险试验显示权,纪律和结构偏见,有利于白人男性的过度代表.
- 包括有色人种和妇女在内的边缘化群体,系统地代表性不足.
结论:
- 目前用于同时发生的PTSD和AUD的RCT缺乏种族和性别多样性.
- 在RCT过程中的偏见导致女性和有色人种的代表性不足.
- 未来的研究必须优先考虑包容性方法,为各种人群开发公平的治疗方法.
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