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Updated: Jun 25, 2026

Detection of Toxin Translocation into the Host Cytosol by Surface Plasmon Resonance
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一种深度学习方法,可以预测细菌ADP-ribosyltransferase毒素

Dandan Zheng1, Siyu Zhou1, Lihong Chen1

  • 1NHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 102629, China.

Bioinformatics (Oxford, England)
|June 17, 2024
PubMed
概括

一个新的深度学习模型,ARTNet,在基因组中准确识别细菌ADP-ribosyltransferase毒素 (bARTTs). 这种工具有助于发现新的BARTT,这对于理解细菌毒性和病原性至关重要.

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相关概念视频

Bacterial Toxins01:12

Bacterial Toxins

Bacterial toxins are sophisticated virulence factors that enable pathogenic bacteria to interact with, invade, and damage host tissues. These toxins fall broadly into two types: protein exotoxins, which are secreted into the environment and target specific host receptors, and lipopolysaccharide endotoxins, which are structural components of the bacterial outer membrane released primarily during bacterial lysis or membrane shedding. Exotoxins generally act more selectively, binding to cell...