对扩展一代生殖毒性研究 (OECD TG 443) 的剂量设置的审查:关于ECHA剂量级选择建议的考虑

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Updated: May 12, 2026

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
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Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants

Published on: March 6, 2018

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Manon Beekhuijzen1, Emily Richmond2, Jason Manton2

  • 1Charles River Laboratories, 's-Hertogenbosch, the Netherlands.

Regulatory toxicology and pharmacology : RTP
|June 17, 2024
PubMed
概括

欧洲化学品署 (ECHA) 对生殖毒性研究的建议可能会通过不充分评估危害和超过最大耐受剂量来损害动物福利和人类安全. 专家敦促ECHA采用经过修订的,以科学为导向的剂量选择方法.

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