处理语言部分与处理工具和身体部位共享神经遗传基础
Haojie Wen1,2,3,4, Dahui Wang1,3,4, Yanchao Bi5,2,3,6
1State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China.
eNeuro
|June 17, 2024
概括
遗传对大脑的影响.
科学领域:
- 神经科学,遗传学,进化生物学
背景情况:
- 人类语言依赖于一个复杂的,分布式的大脑网络.
- 了解这种网络的遗传基础对于进化见解至关重要.
- 以前的研究表明,语言与工具和社会线索等对象领域的潜在共同进化.
研究的目的:
- 为了调查大脑对语言反应的基因机制是否与对象领域的基因机制重叠.
- 探索对语言,工具,面部和身体部位的神经处理的共同或独特的遗传影响.
主要方法:
- 分析了来自人类结合体项目双胞胎数据集 (单胞胎和双胞胎) 的功能磁共振成像 (fMRI) 数据.
- 研究了在涉及各种对象领域的语言和工作记忆任务期间对大脑活动的遗传影响.
- 使用来自艾伦人类大脑图谱的人类基因表达特征来证实这些发现.
主要成果:
- 识别了对语言处理的额头,和皮层下区域的受遗传影响的大脑区域.
- 双边基底 (脊尾) 显示出处理语言,工具和身体部位的共同遗传基础.
- 右上旋表现出语言和工具处理的共同遗传基础.
结论:
- 语言神经过程表现出异质的遗传模式.
- 揭示了语言与工具和身体部位的加工之间的共同遗传起源.
- 提供了关于语言,工具使用和社会功能之间的进化关系的见解.
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