固体天然和有机肥中的兽用抗生素残留物 - - 方法开发和样本分析
Ewelina Patyra1, Zbigniew Osiński2, Krzysztof Kwiatek2
1Department of Hygiene of Animal Feedingstufs, National Veterinary Research Institute, Pulawy, Poland. ewelina.patyra@piwet.pulawy.pl.
概括
兽医抗生素污染了超过38%的天然肥料和37%的有机肥料,造成环境和健康风险. 一种新的验证方法在肥料中检测到21种抗菌物质.
科学领域:
- 农业科学 农业科学
- 环境化学环境化学
- 分析化学 分析化学
背景情况:
- 牲畜便被广泛用作天然和有机肥料.
- 便中的兽医抗生素可以污染土壤,损害微生物,对人类和动物健康构成风险.
- 需要一种强大的分析方法来检测肥料中的这些污染物.
研究的目的:
- 开发和验证一种检测固体天然和有机肥料中的21种抗菌物质的方法.
- 评估这些肥料中抗生素污染的发生率和水平.
主要方法:
- 从肥料样本中提取了抗生素,使用了乙和McIlvain-Na2EDTA缓冲剂.
- 提取物使用固相提取 (SPE) 在Strata-X弹上进行净化.
- 分析是使用超高性能液体染色学-并联质谱法 (UHPLC-MS/MS) 进行的.
主要成果:
- 开发的UHPLC-MS/MS方法显示了高回收率 (93.6-116.6%) 和线性 (50-1000μg/kg).
- 超过38%的天然肥料和37%的加工有机肥料被抗生素污染.
- 多西环素是一种常见的污染物,度高达每公斤几十毫克.
结论:
- 开发和验证的分析方法有效量化固体肥料中的抗菌物质.
- 抗生素污染在自然和有机肥料中普遍存在,突出了潜在的环境和健康问题.
- 这些发现强调需要监测农业投入中的抗生素残留物.
更多相关视频
05:46Identification of Pharmaceuticals in The Aquatic Environment Using HPLC-ESI-Q-TOF-MS and Elimination of Erythromycin Through Photo-Induced Degradation
Published on: August 1, 2018
13.1K
04:17Analysis of Organochlorine Pesticides in a Soil Sample by a Modified QuEChERS Approach Using Ammonium Formate
Published on: January 20, 2023
3.1K
相关概念视频
00:57Antibiotic Selection
Overview
01:27Microorganisms in Agriculture and Food industry
Microorganisms play a crucial role in agriculture and the food industry, contributing to soil fertility, crop protection, and food production. Their functions range from nitrogen fixation and biopesticide production to fermentation and food preservation, making them indispensable to sustainable farming and food safety.Role in AgricultureNitrogen-fixing bacteria, such as Rhizobium (symbiotic) and Azotobacter (free-living), convert atmospheric nitrogen into ammonia through biological nitrogen...
01:27Production of Antibiotics
Penicillin, one of the earliest and most widely used antibiotics, is produced industrially by the filamentous fungus Penicillium chrysogenum. Large stirred-tank bioreactors ranging from tens to hundreds of thousands of liters maintain tightly controlled temperature, pH, and dissolved oxygen conditions to support fungal metabolism and maximize antibiotic yield. Penicillin is a secondary metabolite, synthesized primarily during the stationary growth phase, which requires a carefully managed...