复合电解质眼内灌溶液对白内障患者在手术后的视力恢复产生了比林格尔乳酸盐溶液更好的效果
Chen Guo1, Fang Tian1, Dazhuang Ren1
1Department of Cataract, Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, 251 Fukang Road, Nankai District, Tianjin, 300000, China.
International ophthalmology
|June 17, 2024
概括
复合电解质眼内灌注溶液 (CEIIS) 在白内障手术中提供了优越的短期视力恢复,与林格乳酸 (RL) 相比,特别适用于糖尿病患者. CEIIS还有助于减少手术后的黄斑变化.
科学领域:
- 眼科医生 眼科 眼科
- 生物材料科学 生物材料科学
- 医疗器械 医疗器械
背景情况:
- 眼内灌溶液在白内障手术中至关重要.
- 了解它们对眼睛参数的影响对于优化手术结果至关重要.
研究的目的:
- 为了比较复合电解质眼内灌液 (CEIIS) 和林格乳酸盐 (RL) 对光学连贯性断层扫描 (OCT) 和光学质量分析系统 (OQAS) 参数的影响.
- 研究这些解决方案对白内障患者视力恢复的影响,包括患有糖尿病 (DM) 的患者.
主要方法:
- 一项随机对200名白内障患者进行的研究,分为CEIIS和RL组.
- 使用CEIIS或RL进行化与前腔灌.
- 使用OCT和OQAS II.评估中央黄斑厚度 (CMT),高反射焦点 (HF),调制转移函数 (MTF) 切断值,斯特勒比率 (SR),客观散射指数 (OSI),OQAS值 (OVs) 和最佳校正视力敏度 (BCVA).
- 患者被分为糖尿病 (DM+) 和非糖尿病 (DM-) 亚组.
主要成果:
- 无论是CEIIS还是RL都改善了术后视觉质量,由增加的CMT,MTF切线,SR,OV和减少的OSI证明.
- 与RL相比,CEIIS在DM+患者中显示出优异的短期视力恢复,减少黄斑HF,以及较慢的CMT增加.
- 两种解决方案之间没有观察到显著的长期视力改善差异.
结论:
- 与RL相比,CEIIS提供了更好的短期视力恢复,并减轻了老年糖尿病白内障患者的黄斑变化.
- 这两种灌解决方案都提高了术后视觉质量,但CEIIS为糖尿病患者提供了特定的优势.
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