在2型糖尿病患者中,加速计推导的身体活动和死亡率
Zhi Cao1,2, Jiahao Min1, Han Chen1
1School of Public Health, Hangzhou Normal University, Hangzhou, China.
Nature communications
|June 17, 2024
概括
定期体力活动 (PA) 显著降低了2型糖尿病 (T2D) 患者的死亡率. 运动的强度和持续时间更大,与所有原因,癌症和心血管疾病死亡率的风险较低有关.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 众所周知,身体活动 (PA) 可以降低糖尿病死亡率.
- 之前的研究依赖于不准确的自我报告数据,可能限制推.
- 客观测量对于在2型糖尿病 (T2D) 中准确评估PA至关重要.
研究的目的:
- 调查客观测量PA持续时间和强度与T2D患者死亡率之间的关联.
- 提供基于证据的见解,以完善T2D管理的PA临床指南.
主要方法:
- 来自英国生物库的19,624名2型糖尿病患者的前性队列研究.
- 在7天内,使用手腕穿戴的加速度计客观测量PA.
- 平均随访时间为6.9年,以评估死亡率的结果.
主要成果:
- 在PA持续时间和所有原因/癌症死亡风险之间观察到L形关联.
- 在PA持续时间和心血管疾病死亡风险之间发现了负线性关联.
- 死亡的很大比例归因于低水平的光 (12.7%),中度的 (15.8%) 和强烈的 (22.3%) PA.
结论:
- 客观测量的PA持续时间和强度与T2D的死亡率密切相关.
- 临床指南应强调增加PA持续时间和强度对T2D患者的好处.
- 研究结果支持促进更高水平的体育活动的价值,以改善2型糖尿病的生存率.
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