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Updated: Jun 23, 2025

Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells
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Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells

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RUNX1调节MCM2/CDC20以促进COAD的进展,这种进展是由USP31的二基化改变的

Wei Tian1,2, Jingyuan Zhao3, Xinyu Zhang1,2

  • 1The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Scientific reports
|June 17, 2024
PubMed
概括

RUNX1在结肠腺癌 (COAD) 中高度表达,这是一种缺乏生物标志物的癌症. 沉默RUNX1抑制COAD细胞的增殖和迁移,这表明它是一个潜在的治疗点.

关键词:
结肠腺癌结肠腺癌.预测 预后 预测 预测在RUNX1中,使用RUNX1.转录因子 转录因子美国31美金

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