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Updated: Jun 23, 2025

A Technique to Simultaneously Visualize Virus-Specific CD8+ T Cells and Virus-Infected Cells In situ
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A Technique to Simultaneously Visualize Virus-Specific CD8+ T Cells and Virus-Infected Cells In situ

Published on: August 13, 2009

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淋巴结中的明显的SIV特异性CD8+ T细胞表现出同时的效应因子和干状特征,并与有限的SIV持久性有关

Zachary Strongin1, Laurence Raymond Marchand1, Claire Deleage2

  • 1Division of Microbiology and Immunology, Emory National Primate Research Center, Emory University, Atlanta, GA, USA.

Nature immunology
|June 17, 2024
PubMed
概括

研究人员确定了一种特定的CD8+T细胞群 (TOXhiTCF1+CD39+),在控制猿类免疫缺陷病毒 (SIV) 和人类免疫缺陷病毒 (HIV) 中发挥着至关重要的作用. 这些细胞表现出中间效应体和干状特征,有助于减少病毒载量和持久性.

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Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant08:52

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