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Updated: Jun 12, 2026

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma
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VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma

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杜维利西布加罗米德素治疗复发性/耐药T细胞淋巴瘤:一项1b/2a期试验

Steven M Horwitz1,2, Ajit J Nirmal3, Jahan Rahman4

  • 1Lymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. horwitzs@mskcc.org.

Nature medicine
|June 17, 2024
PubMed
概括

将杜维利西布 (PI3K-δγ 抑制剂) 与罗米德结合使用,在T细胞淋巴瘤 (TCL) 中显示出更好的疗效和更低的毒性. 这种组合疗法为治疗复发性/耐药性TCL提供了一个有希望的策略,特别是在特定亚型中.

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