母亲抑郁和焦虑对儿童免疫状况的影响:一项前性队列研究
Shannon E MacDonald1,2, Manisha Dhungana3, Victoria Stagg4
1Faculty of Nursing, University of Alberta, Edmonton, Canada. smacdon@ualberta.ca.
概括
母亲的抑郁和焦虑不会影响儿童的疫苗接种. 然而,低收入和家庭迁移可能会影响免疫接种计划,因此需要为有风险的家庭提供预先指导.
科学领域:
- 围产期心理健康问题
- 儿童免疫接种 儿童免疫接种
- 公共卫生 公共卫生
背景情况:
- 母亲的抑郁和焦虑会对孩子的发育和出生结果产生负面影响.
- 关于母亲心理健康对儿童免疫坚持的影响的数据有限.
- 这项研究调查了围产期母亲心理健康与延迟儿童疫苗接种之间的联系.
研究的目的:
- 确定产前期母亲抑郁和焦虑对儿童疫苗接种计划长期延迟的影响.
- 为了确定与延迟免疫坚持相关的潜在风险因素.
主要方法:
- 一项前性队列研究分析了阿尔伯塔省卡尔加里的2,762名孕妇的相关调查和行政数据.
- 在产前 (怀孕25周之前) 和产后 (4个月) 收集的数据.
- 多变量逻辑回归用于评估母亲心理健康与长期免疫延迟之间的关联,控制共变量.
主要成果:
- 母亲抑郁或焦虑与特定疫苗 (DTaP-IPV-Hib,MMR/MMRV) 或所有常规儿童疫苗联合的长期延迟没有显著关联.
- 加拿大出生的母亲和来自低收入家庭的孩子的长期免疫延迟的几率更高.
- 在母亲焦虑和延迟接种疫苗计划之间没有发现统计学意义上的关联.
结论:
- 医疗保健提供者可以放心地说,母亲的抑郁和焦虑似乎不会影响对常规儿童免疫接种的承诺.
- 低收入和家庭流动性被确定为影响疫苗计划遵守的潜在因素.
- 预期性指导对于面临社会经济挑战或经常搬家的家庭来说可能是有益的,以确保及时接种疫苗.
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