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Updated: Jun 23, 2025

Determining 3'-Termini and Sequences of Nascent Single-Stranded Viral DNA Molecules during HIV-1 Reverse Transcription in Infected Cells
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Determining 3'-Termini and Sequences of Nascent Single-Stranded Viral DNA Molecules during HIV-1 Reverse Transcription in Infected Cells

Published on: January 30, 2019

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复原病毒PBS细分序列和结构:编排早期和晚期复制事件

Xiao Heng1, Amanda Paz Herrera2, Zhenwei Song3

  • 1Department of Biochemistry, University of Missouri, Columbia, MO, 65211, USA. hengx@health.missouri.edu.

Retrovirology
|June 17, 2024
PubMed
概括

艾滋病毒-1 5'未翻译区域 (UTR) PBS部分形成了一个复杂的结构,与宿主因子 (如RNA酶A (RHA)) 相互作用. 这种相互作用对于病毒复制,RNA修饰和双相蛋白转化至关重要,为潜在的治疗标提供了潜在的治疗标.

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