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识别新型PD-1/PD-L1小分子抑制剂:虚拟查,合成和体外表征

Tingting Wu1,2, Hu Cheng1, Lijie Sima3

  • 1Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, China.

Journal of enzyme inhibition and medicinal chemistry
|June 18, 2024
PubMed
概括

研究人员确定了ZDS20,一种针对PD-1/PD-L1通路的新型小分子抑制剂. 这种化合物表现出强烈的活性,为癌症免疫疗法开发提供了抗体的有希望的替代品.

关键词:
免疫检查站检查站这是一种PD-1/PD-L1抑制剂.分子动力学模拟模拟虚拟选 虚拟选 虚拟选

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