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相关概念视频

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Desmosomes01:05

Desmosomes

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The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are  essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein...
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Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
440
Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

619
The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's...
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Autoimmune Disorders01:29

Autoimmune Disorders

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Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
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相关实验视频

Updated: Jun 23, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

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硬化皮质和类似硬化皮质的综合征

Katarzyna Romanowska-Próchnicka1, Martyna Dziewit1, Aleksandra Lesiak2

  • 1Department of Connective Tissue Diseases, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.

Frontiers in immunology
|June 18, 2024
PubMed
概括
此摘要是机器生成的。

系统性硬化症涉及渐进性纤维化. 类似硬化症的综合征模仿这种情况,但源于各种原因,如自身免疫性疾病,遗传或毒素,需要不同的诊断和管理.

关键词:
遗传学 遗传学 遗传学 遗传学 是一个莫菲亚 (Morphea) 是一个形象.硬化皮质硬化皮质 (scleroderma) 是一种疾病.类似于硬化性皮肤的综合征.炎症/自身免疫的综合征.系统性硬化症 系统性硬化症这是一种有毒的有毒物质.

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科学领域:

  • 类风湿病学 类风湿病学
  • 皮肤病学 皮肤病学
  • 内部医学 内部医学

背景情况:

  • 系统性硬化症是一种纤维结合组织疾病,影响皮肤和内脏.
  • 皮质硬化也可能是其他疾病的结果,称为硬化性皮质类似综合征.
  • 这些综合征与全身性硬化症具有相同的临床特征,但有不同的病因.

研究的目的:

  • 审查有关硬化样综合征的文献.
  • 为了区分这些综合征与全身性硬化症.
  • 概述它们的诱导因素,病变发生,临床表现,诊断和治疗.

主要方法:

  • 关于类硬化症类似综合征的文献综述.
  • 对病因类别的分析:炎症性/自身免疫性,遗传性,代谢性,有毒性,药物诱导性,职业性,瘤性和沉积性疾病.
  • 与系统性硬化症进行比较分析.

主要成果:

  • 类似于硬化症的综合征包括一系列模仿系统性硬化症的疾病.
  • 病因有多种,包括自身免疫性,遗传性,代谢性,有毒性,药物诱导性,职业性,瘤性和沉积性疾病.
  • 每一种综合征都会带来独特的诊断和治疗挑战,与系统性硬化症不同.

结论:

  • 从系统性硬化症到硬化样综合征的准确区分对于适当的患者管理至关重要.
  • 了解不同的病因是针对性诊断和治疗的关键.
  • 进一步研究特定的类硬化症类似综合征可以改善临床结果.