茶和咖啡消费与急性中风风险:中风间的研究
Andrew Smyth1,2, Graeme J Hankey3, Peter Langhorne4
1Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, ON, Canada.
概括
高咖啡摄入量增加了中风风险,而茶饮则与较低的中风几率有关. 每天将咖啡限制在五杯以下,可能有助于降低中风风险.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 神经学 神经学
背景情况:
- 卒中是全球死亡和残疾的主要原因之一.
- 每日茶和咖啡的消费是广泛的习惯,代表了人口层面的显著暴露.
- 了解茶/咖啡摄入量与中风之间的关系对于公共卫生战略至关重要.
研究的目的:
- 调查茶和咖啡消费与中风风险之间的全球关联.
- 为未来的中风预防干预产生假设.
- 提供有关饮料消费和中风的公共卫生建议的信息.
主要方法:
- INTERSTROKE研究是一项大型国际病例控制研究,包括来自32个国家的13,462例中风病例和13,488例对照.
- 参与者报告了每天摄入咖啡,绿茶,黑茶和其他茶的量.
- 多变量条件逻辑回归分析了饮料摄入量和中风之间的关联,计算了几率比率 (OR) 和95%置信区间 (CI).
主要成果:
- 高咖啡消费 (每天超过4杯) 与所有中风 (OR=1.37) 和缺血性中风 (OR=1.32) 的几率增加有关.
- 低至中度咖啡摄入量与中风没有显著关联.
- 茶的消费,特别是较高的摄入量,与所有中风 (OR=0.81) 和缺血性中风 (OR=0.81) 的几率降低有关.
结论:
- 高咖啡消费量 (≥5杯/天) 与中风风险更高有关.
- 茶饮似乎具有保护作用,与降低中风风险有关.
- 减少高咖啡摄入量可能是降低中风风险的潜在策略.
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