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Knee Joint

Knee Joint

The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...

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Updated: Jun 23, 2025

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Published on: July 22, 2021

[在不同年龄段进行全膝关节置换]

T Jianlu¹, L Feng², C Wentao³

¹Volgograd State Medical University, Volgograd, Russia.

|June 18, 2024

概括

此摘要是机器生成的。

全膝关节置换改善了所有年龄段的疼痛和生活质量. 然而,较年轻的患者 (<55岁) 与老年人相比,经过手术后的疼痛和生活质量较差.

关键词:

年龄组年龄组.膝关节关节的关节是什么?骨关节炎是一种关节炎.整体膝关节置换整体膝关节置换

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Last Updated: Jun 23, 2025

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科学领域:

整形外科手术整形外科手术
生物医学工程生物医学工程
康复医学康复医学康复医学

背景情况:

膝关节关节炎显著影响患者的生活质量.
全膝关节置换 (TKR) 是对末期膝关节关节炎的常见手术.
长期结果和TKR的年龄相关疗效需要进一步研究.

研究的目的:

评估在不同年龄的人口统计数据中,在全膝关节置换 (TKR) 后的1年疗效和生活质量结果.
为了确定TKR后患者报告结果的年龄特异性差异.

主要方法:

研究了一组由134名接受单边初级全膝关节置换术的患者组成的队列.
进行了膝关节损伤和骨关节炎结局得分 (KOOS) 和SF-36问卷调查.
患者报告的结局包括疼痛,功能和生活质量被评估为手术前和手术后 (1年).

主要成果:

年轻的患者 (<55岁) 呈现出较低的基线KOOS疼痛,功能和生活质量 (QoL) 评分.
在TKR后一年,年轻的患者报告了与老年患者 (>65岁) 相比,疼痛,功能和QoL的KOOS得分明显较差.
年龄被确定为术后疼痛的重要预测因素,但不是功能性结果.

结论:

在所有年龄组中,全膝关节置换显示出疼痛,功能和生活质量的显著改善.
年轻的TKR患者 (<55岁) 报告了更严重的手术前疼痛和更差的生活质量,以及不太有利的1年术后结果.
这些发现强调了在临床决策和管理患者对TKR的期望时考虑与年龄相关的因素的重要性.