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Updated: Jun 23, 2025

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
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Published on: August 22, 2018

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发现一个azabicyclo[2.1.1]hexane Piperazinium盐,并通过重新排列在药物化学中的应用

Chi He1, Xiaochu Ba1, Hunter P Shunatona1

  • 1Small Molecule Drug Discovery, Bristol Myers Squibb, 10300 Campus Point Drive, Suite 100, San Diego, California 92121, United States.

Organic letters
|June 18, 2024
PubMed
概括

我们通过重新排列发现了一种新的azabicyclo[2.1.1]hexane piperazinium盐. 这种稳定的化合物充当了一种多功能电友,用于合成候选药物,包括雄激素受体降解剂.

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