日光节约时间的转换和心脏病发作风险
Anke Hurst1, Peter Morfeld, Philip Lewis
1Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, University Hospital of Cologne, Cologne, Germany.
Deutsches Arzteblatt international
|June 18, 2024
概括
过渡到夏令时可能会增加急性心肌梗塞 (AMI) 风险,特别是在春天. 需要进一步的研究来证实这一关联并了解其影响.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 节日时间 (DST) 的转变与潜在的健康风险有关.
- 在DST变化后,昼夜节律的扰乱和睡眠剥夺可能会增加急性心肌梗塞 (AMI) 的风险.
- 这项研究扩展了关于AMI风险和DST的唯一现有的元分析.
研究的目的:
- 系统地审查和元分析DST过渡后的几周内AMI的频率.
- 评估DST变化与急性心肌梗塞风险之间的关联.
- 确定潜在的异质性和未来研究领域.
主要方法:
- 一个系统的审查和元分析,包括元回归和灵敏度分析.
- 在八个数据库中进行文献搜索,截至2023年9月,作者可以联系作者以获取更多数据.
- 使用纽卡斯尔-太华尺度评估研究质量.
主要成果:
- 包括来自10个国家的12项研究;其中9项具有足够的质量,3项具有良好的质量.
- 在DST发作 (春季) 后,观察到AMI的1.04的汇总相对风险 (RR),具有中等的异质性.
- 在夏令时偏移 (秋季) 后发现了1.02的聚合RR,具有中等的异质性.
结论:
- 有证据表明,在春季的冬季时间过渡后,AMI的风险可能会增加.
- 在支持春季过渡风险的研究中存在中等到明显的异质性.
- 建议采用不连续性回归和安慰剂测试等方法进行进一步的研究,以获得更清晰的关联.
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