在UPLC-Q-TOF-MS/MS的基础上,从Chaetomium cochliodes中准地发现了切托明类似物

Jian-Zi Liu1, Yan-Duo Wang1, Hui-Qi Fang1

  • 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, People's Republic of China.

PubMed
概括

从Chaetomium cochliodes真菌中净化了两种新型化合物,即chetocochliodin M和N. 一些化合物对癌症细胞系表现出显著的细胞毒性活性.