在患有糖尿病的年轻人中识别并发症 糖尿病酸性酸症与高血糖超状况相比
概括
患有糖尿病的年轻人的超度显著增加了急性并发症,比如精神状态的改变和急性损伤,而不是单独的糖尿病酸性脂肪酸症. 需要进一步的研究,以防止这些严重的结果.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 代谢障碍 代谢障碍 代谢障碍
- 关键护理医学 关键护理医学
背景情况:
- 糖尿病酸性脂肪酸 (DKA) 和超性状态是年轻人严重的高血糖紧急情况.
- 对单独的DKA和超状况之间的并发症进行比较对于了解疾病严重程度至关重要.
研究的目的:
- 为了比较患有单独的DKA的儿科患者和患有超状况的儿科患者的住院并发症.
- 确定与高血糖紧急情况严重程度增加相关的风险因素.
主要方法:
- 对两年内入院的1-20岁患者的医疗记录的回顾性审查.
- 评估结果,包括停留时间,精神状态变化 (AMS) 和急性损伤 (AKI).
- 分析包括患有DKA的患者,高血糖超状况 (HHS) 和高状DKA.
主要成果:
- 患有高胞状况 (高胞DKA和HHS) 的年轻人经历了更长的住院时间,更大的液体球体和更多的PICU入院.
- 超大的年轻人患AKI和AMS的风险明显增加.
- 较高的血清度与AKI的几率增加相关,而新发糖尿病与已确定的糖尿病相比,与较低的几率相关.
结论:
- 糖尿病青少年的超度加剧了与孤立的DKA相比的急性并发症.
- 迫切需要进行更大规模的研究,以制定预防儿科高血糖紧急情况急性并发症的策略.
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