左束分支阻塞对心声回声学冠状动脉流量评估的影响:系统性审查
Davide Donelli1,2, Michele Antonelli3, Filippo Luca Gurgoglione1,2
1Department of Medicine and Surgery, University of Parma, Parma, Italy.
Echocardiography (Mount Kisco, N.Y.)
|June 18, 2024
概括
通过心声学评估的冠状动脉流量储量 (CFR) 能够有效地识别左束分支阻塞 (LBBB) 患者的显著冠状动脉疾病 (CAD). 这种非侵入性方法有助于对这种复杂的患者群体进行风险分层和临床决策.
科学领域:
- 心脏病学 心脏病学
- 诊断成像 诊断成像 诊断成像
- 非侵入性心血管评估
背景情况:
- 左捆支部阻塞 (LBBB) 复杂化了冠状动脉疾病 (CAD) 的评估.
- 冠状动脉流量储备 (CFR) 是心肌 perfusion 的一个关键指标.
- 心声谱提供了一种非侵入性的方法来评估心率.
研究的目的:
- 在LBBB患者中系统地审查心声回声学衍生的CFR的诊断和预后效用.
- 评估LBBB对CFR测量的影响及其与CAD的相关性.
- 评估CFR作为LBBB患者风险分层的工具.
主要方法:
- 在PubMed,EMBASE,科学网,Scopus和谷歌学者的系统文献搜索到2024年3月.
- 包括六项符合PRISMA标准的观察性研究.
- 在多种不同的LBBB群体中分析心声回声记录的CFR协议.
主要成果:
- 与对照组相比,患有LBBB和显著的左前下降动脉狭窄 (LAD) 的患者显示压力峰值透析速度和CFR显著降低.
- 聚合分析表明,具有显著LAD狭窄症的患者的CFR显著下降 (MD = -0.60).
- 心声回路率评价在确定LBBB群体中临床显著的CAD方面表现出有效性.
结论:
- 基于心声谱的CFR评估是一种临床相关的非侵入性工具,用于评估LBBB患者的CAD.
- CFR测量有助于心血管风险分层,并在LBBB存在时指导临床决策.
- 为了在LBBB患者中获得最佳应用,需要对CFR测量协议进行标准化.
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