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Updated: Jun 23, 2025

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
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通过构成约束来设计衍生物作为α2A-腺素受体选择性激动剂

Xucheng Lv1, Peilan Zhou1, Xuehong Qiao1,2

  • 1Beijing Institute of Pharmacology and Toxicology, Haidian District, Beijing 100850, China.

Journal of medicinal chemistry
|June 18, 2024
PubMed
概括

研究人员开发了具有提高选择性的新型α2A-腺受体 (α2A-AR) 激动剂. 化合物A9和B9显示出高强度和选择性,比现有药物具有潜在的治疗优势.

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