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Updated: Jun 23, 2025

G Protein-selective GPCR Conformations Measured Using FRET Sensors in a Live Cell Suspension Fluorometer Assay
09:12

G Protein-selective GPCR Conformations Measured Using FRET Sensors in a Live Cell Suspension Fluorometer Assay

Published on: September 10, 2016

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基于形状和激活的BRET传感器不同地报告GPCR-G蛋白合

Shane C Wright1,2,3, Charlotte Avet2, Supriya A Gaitonde1,2

  • 1Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada.

Science signaling
|June 18, 2024
PubMed
概括

不同的生物传感器类型显示了G蛋白结合受体 (GPCR) 信号传输的复杂性. 实验设计,包括G蛋白子单元选择和表位标记,对评估GPCR-G蛋白合特异性产生重大影响.

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