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Updated: Jun 23, 2025

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay
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Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay

Published on: March 10, 2020

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门环在β-arrestin-1构造动态和化受体相互作用中的作用

Kiae Kim1, Janbolat Ashim2, Donghee Ham1

  • 1School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.

Structure (London, England : 1993)
|June 18, 2024
PubMed
概括

阿雷斯调节了G蛋白结合受体 (GPCR) 脱敏. 在β-arrestin-1,特别是K294中的关键门环残留物,对于像V2Rpp这样的化GPCRs的结合至关重要,影响受体调节.

关键词:
在GPCR中化C尾部.在HDX-MS中使用HDX-MS.模拟MD的模拟方法逮捕 逮捕 逮捕 逮捕门的循环环,门的循环.

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