复发性红疹多形状状反应是由于经常暴露于毒常春藤的次要反应
Smrithi Mani1, Lisa Morris2, Susan J Bayliss2
1Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Pediatric dermatology
|June 18, 2024
概括
一名14岁的男孩在暴露于毒常春藤后经历了反复的多形红斑样反应. 反应的严重程度与之前的过敏接触性皮肤炎强度相关.
科学领域:
- 皮肤病学 皮肤病学
- 毒理学 毒理学 毒理学
背景情况:
- 过敏接触性皮肤炎是一种常见的延迟过敏反应.
- 毒性草 (toxicodendron radicans) 是过敏接触性皮肤炎的常见原因之一.
研究的目的:
- 报告在暴露于毒常春藤后出现的复发性红斑多形状反应的情况.
- 调查过敏接触性皮肤炎的严重程度和随后的多形红斑样反应之间的关系.
主要方法:
- 一个14岁男孩的案例报告.
- 在3年内观察了三个单独的发作.
- 反应严重程度与先前皮肤炎的相关性.
主要成果:
- 患者经历了三次不同的红血多形状的发作.
- 每次爆发都是在有毒常春藤过敏接触性皮肤炎的发作之后发生的.
- 红斑多形状反应的严重程度反映了初始接触性皮肤炎的严重程度.
结论:
- 反复出现的多形红血类反应可能与重复暴露于毒常春藤有关.
- 毒常春藤过敏接触性皮肤炎的严重程度可以预测随后的红斑多形状反应的严重程度.
相关概念视频
Allergic Reactions
27.3K
Overview
27.3K
Cross-reactivity
31.0K
Overview
31.0K
Allergic Drug Reactions
833
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
833
Hypersensitivities
586
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
586
Toxic Reactions: Overview
966
When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
966
Immunological Memory
590
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
590


