在高氧症下增强心肺呼吸能力的机制与黄尾金鱼的暴露时间不同
Daniel Morgenroth1,2, Tristan McArley1, Javed Khan3,4
1Department of Biological and Environmental Sciences, University of Gothenburg, PO Box 463, Gothenburg 405 30, Sweden.
Proceedings. Biological sciences
|June 18, 2024
概括
环境高氧会通过增加氧气吸收来提高鱼类的有氧性能. 这种增强通过急性改善氧气提取和慢性增加心脏输出与心室生长而发生,有助于弹性.
科学领域:
- 生理学 生理学 生理学
- 环境科学 环境科学
- 水产养殖是水产养殖的一种方式.
背景情况:
- 过氧可以增强鱼类的有氧能力,但机制和持续时间相关的效应尚不清楚.
- 黄尾金鱼 (Seriola lalandi) 的有氧范围在normoxia中是有限的.
研究的目的:
- 在急性和慢性高氧症下研究黄尾金鱼的心肺呼吸功能.
- 确定驱动有氧范围扩张在高氧化的机制.
主要方法:
- 在急性 (~20小时) 和慢性 (3-5周) 期间将鱼暴露在高氧 (~200%的空气和) 中.
- 测量心肺呼吸系统参数,包括最大氧气吸收量 (MO2max) 和心脏输出量.
- 评估心室质量和氧气提取效率.
主要成果:
- 在急性和慢性治疗中,有氧性表现随着高氧化增加.
- 在高氧症中,最大氧气吸收 (MO2max) 增加了约33%.
- 急性高氧化增加了组织的O2提取;慢性高氧化增加了中风体积介导的心脏输出,部分原因是心室生长 (8-12%更大的相对心室质量).
结论:
- 过氧扩大了黄尾金鱼的有氧范围,具有明显的急性和慢性暴露机制.
- 慢性高氧,加上心室可塑性,显著增加心脏输出.
- 过氧可能会增强鱼类对代谢挑战的抵抗力,并改善水产养殖的结果.
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