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吞肌肉质量有助于在经历机械血栓切除术的缺血性中风患者中导致中风后的消化不良

João Pinho¹, Tareq Meyer¹, Beate Schumann-Werner^2,3

¹Department of Neurology, University Hospital RWTH, Aachen, Germany.

Journal of cachexia, sarcopenia and muscle

|June 18, 2024

概括

减少吞肌肉质量与大血管封闭性中风患者的更严重的中风后消化不良和喉残留有关. 这一发现强调肌肉质量是中风后吞困难的关键因素.

科学领域:

神经学神经学
胃肠病学胃肠病学
老年学是指老年学的学科.

背景情况:

神经性失足症是一种常见的中风并发症,影响结果并增加吸气性肺炎的风险.
虽然中风病变特征是已知的决定因素,但影响缺食的非病变因素仍未得到充分研究.
这项研究调查了肌肉质量在中风后吞功能中的作用.

研究的目的:

分析吞和非吞肌肉测量对大血管阻塞中风后吞功能的影响.
为了确定肌肉质量是否能预测缺食症的严重程度和喉残留.
探索影响中风后吞的超出中风病变特征的因素.

主要方法:

对接受机械血栓切除术的缺血性中风患者的前性注册表的回顾性分析.
在入院5天内进行吞的灵活内镜评估 (FEES).
通过CT测量吞和宫非吞肌肉截面面积 (CSA),并计算骨肌肉指数 (SMI). 与FEES参数的相关性,如FOIS和透-吸收尺度.

主要成果:

包括137名患者;中位数年龄74岁,NIHSS中位数12.
吞肌肉CSA和SMI与年龄有显著的相关性.
吞肌肉CSA独立地与更高的FOIS分数 (P=0.029) 和中度至严重的喉残留物 (P=0.036) 的增加有关.
SMI 没有显示与 FEES 参数的独立关联.

结论:

基线吞肌肉质量是中风后消化不良症的一个重要因素.
减少吞肌肉质量独立地与增加的吞障碍严重程度和喉残留物有关.
肌肉质量评估可能会提供关于中风后失调症管理策略的见解.

关键词:

消化不良症消化不良症纤维光学内镜评估吞的情况缺血性中风缺血性中风萨尔科佩尼亚是什么意思萨尔科佩尼亚

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