艾滋病毒感染者的临床认可的睡眠障碍
Jennifer O Lam1,2, Craig E Hou3, Stacey Alexeeff1
1Division of Research, Kaiser Permanente Northern California, Pleasanton, California, USA.
HIV medicine
|June 18, 2024
概括
艾滋病毒感染者 (PWH) 患有更高的睡眠障碍,尤其是失眠. 睡眠呼吸暂停的发病率在PWH中较低,可能是由于艾滋病毒控制较弱的患者的诊断不足.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 传染性疾病传染性疾病.
背景情况:
- 艾滋病毒感染者 (PWH) 被认为更容易受到睡眠障碍的影响.
- 然而,对这一群体中诊断出睡眠障碍的全面了解仍然有限.
研究的目的:
- 在接受治疗的艾滋病毒感染者中调查临床诊断的睡眠障碍的全谱.
- 为了比较艾滋病毒感染者 (PWH) 和没有艾滋病毒感染者 (PWoH) 之间的睡眠障碍发病率.
主要方法:
- 一个回顾性队列研究,在一个大型医疗保健系统中比较9076 PWH和205,178 PWoH.
- 诊断出睡眠障碍 (整体,失眠,睡眠呼吸暂停) 的发生率被计算并使用调整后的发生率比率 (aIRR) 进行比较.
- 分析包括根据艾滋病毒管理状况进行分层 (管理良好与管理不良).
主要成果:
- 与PWoH相比,PWH的整体睡眠障碍发生率较高 (aIRR=1.19).
- 在PWH中,失眠的发生率明显高 (aIRR=1.56),而睡眠呼吸暂停的发生率较低 (aIRR=0.90).
- 与PWoH相比,未得到最佳管理的PWH显示睡眠呼吸暂停发病率较低 (aIRR=0.79).
结论:
- 艾滋病毒感染者的睡眠障碍发病率很高,失眠是最常见的诊断.
- 在PWH中观察到的睡眠呼吸暂停发病率较低,因此需要进一步调查,特别是关于艾滋病毒管理效率较低的人群潜在的不足诊断.
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