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多发性硬化症的认知变化和神经放射学变化与时间的相关性:系统性审查和元分析

Leila Simani¹, Leila Molaeipour², Saeid Kian³

¹Cognitive Neuroscience Division, Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.

Journal of neurology

|June 18, 2024

概括

纵向研究表明,多发性硬化症 (MS) 的认知变化与MRI检测到的大脑变化有关. 具体来说,符号数字模式测试 (SDMT) / 定时听力序列加法测试 (PASAT) 和口头流利与T2损伤体积和缩相关.

科学领域:

神经成像和认知科学认知科学
神经学和临床研究.

背景情况:

对多发性硬化症 (MS) 中的神经成像和认知变化的纵向研究很少.
了解MS中神经放射学和认知变化之间的关系需要进行系统的审查.

结论:

在MS中认知能力下降,特别是SDMT/PASAT表现和口语流性,与T2LV和大脑缩有关.
研究结果强调了大脑结构变化与MS认知功能之间的联系.
由于现有研究的局限性,需要进一步进行高质量的研究.

关键词:

改变改变改变认知能力认知能力认知能力损失损失的情况这就是为什么MRI是MRI.多发性硬化症是多发性硬化症.

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