运动,丸激素,维生素D,和蛋白质对老年男性的有益影响-一项随机临床试验
Mette Midttun1, Karsten Overgaard2, Bo Zerahn3
1Medical Department O, University Hospital of Copenhagen, Herlev Hospital, Herlev, Denmark.
Journal of cachexia, sarcopenia and muscle
|June 18, 2024
概括
将氨酸未酸 (TU) 注射与渐进式力量训练和营养补充剂相结合,显著改善了老年男性的运动能力和生活质量. 这种干预改善了身体功能,减少了疲劳,没有显著的不良影响.
科学领域:
- 老年学是一门学科.
- 内分泌学 在内分泌学.
- 运动医学 运动医学
背景情况:
- 老年人中跌倒是全球日益关注的问题,导致伤害,残疾和死亡.
- 患有低丸激素和运动问题的老年男性尤其容易受到伤害.
- 这项研究解决了改善健康和预防这一人口群体下降的干预措施的需要.
研究的目的:
- 评估非酸盐 (TU) 注射,渐进性力量训练和营养补充剂在改善70岁及以上男性健康状况方面的有效性.
- 评估这些干预措施对移动性,肌肉力量和生活质量的综合影响.
- 为了确定组合干预方法的安全概况.
主要方法:
- 这是一项为期20周的单中心,随机化,安慰剂控制,双盲试验,涉及148名70岁以上的男性,他们患有低正常至低丸激素和运动问题.
- 参与者被分为四组:TU治疗,使用补充剂 (,维生素D,蛋白质) 进行渐进性抵抗训练,联合治疗或对照组.
- 主要结果测量是30秒的椅子站测试,评估下肢肌肉力量和跌倒风险.
主要成果:
- 与对照组相比,组合干预组在30秒的椅子站立测试中显著改善 (P=0.003).
- 组合组的参与者报告说,生活质量有所改善,疲劳减少,腿部脂肪减少.
- 单独的非酸治疗也导致了关节和腿部脂肪的减少,在不同组中没有显著增加的不良反应.
结论:
- ,,维生素D,蛋白质和渐进性抵抗训练的联合治疗有效地改善了老年男性的身体功能,肌肉力量和生活质量,这些男性的和运动问题较低.
- 干预成功地减少了疲劳和腿部脂肪,同时增加了RR间隔的变化.
- 治疗方案被发现是安全的,没有报告显著的不良影响.
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