关于年轻人中风发病率和风险因素的国际视角:范围审查
Dinah Amoah1, Matthew Schmidt2, Carey Mather3
1School of Health Sciences, University of Tasmania, Launceston, Australia. dinah.amoah@utas.edu.au.
BMC public health
|June 18, 2024
概括
年轻人 (≤30岁) 全球中风发病率正在上升,但有关风险因素和发病率的数据仍然很少. 本综述综合了关于围产,儿科和年轻成年人中风风险因素以及全球中风发病率的证据.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 全球中风发病率在年轻人群中不断增加.
- 关于30岁及以下人中风发病率和风险因素的数据有限.
- 本综述重点关注的是围产,儿科和年轻成人中风.
研究的目的:
- 检查全球关于30岁及以下人中风发病率和风险因素的证据.
- 确定年轻中风人口中不同年龄组的共同风险因素.
主要方法:
- 一个由乔安娜·布里格斯研究所的方法指导的范围审查.
- 在2022年3月23日对Medline,Embase,PsycINFO和CINAHL数据库进行系统搜索.
- 包括所有研究设计报告的发病率和风险因素的中风在个人 ≤30年在过去十年内.
主要成果:
- 包括471篇文章,其中大多数专注于风险因素 (63%) 而不是发病率 (37%).
- 发病率数据报告是异质的,阻止了合成.
- 确定了关键的风险因素:围产期 (感染,心脏病,产后因素),儿科 (血管疾病,感染,心脏病) 和年轻成人 (慢性疾病,如糖尿病,血管疾病,心脏病).
结论:
- 在围产,儿科和年轻成年人年龄组中,中风风险因素有很大差异.
- 进一步的流行病学研究对于了解年轻人中风发病率和风险因素至关重要.
- 为了进行全球比较,需要对特定年龄段的发病率数据进行标准化报告.
相关概念视频
Regulation of Stroke Volume
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Stroke: Introduction and Types
A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...
Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Ischemic Stroke ll: Pathophysiology
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...


