在受冲击的第三手术中比较周围神经和全身甲松的使用,以麻醉的持续时间和术后的投诉:一个受控的随机观察性研究
Doğan Ilgaz Kaya1, Ahmet Aktı2
1Faculty of Dentistry, Oral and Maxillofacial Surgery, Karamanoglu Mehmetbey University, Karaman, 70200, Turkey. doganilgaz@kmu.edu.tr.
BMC oral health
|June 18, 2024
概括
静脉注射 (IV) 德克萨米他 (DXN) 延长了麻醉,并在受冲击的第三 (ITM) 手术后减少了疼痛和胀. 围 (PN) DXN减少了胀,但增加了疼痛,表明IV在管理ITM手术结果方面优越.
科学领域:
- 口腔和牙面部外科手术
- 药理学 药理学是指药理学的学科.
- 麻醉学 麻醉学
背景情况:
- 受影响的第三 (ITM) 提取经常导致术后疼痛,胀和功能限制.
- 甲 (DXN) 是一种类固醇,在口腔手术中用于减轻疼痛和炎症.
- 研究最佳的DXN注射途径,如静脉注射 (IV) 和周围神经 (PN),以及下膜神经阻塞 (IANB) 对于ITM手术至关重要.
研究的目的:
- 为了比较静脉注射 (IV) 和周围神经 (PN) 德克萨米他 (DXN) 给药在经受影响的第三 (ITM) 提取后的术后结果管理中的疗效.
- 评估IV和PN DXN对麻醉持续时间,术后疼痛和的影响.
- 确定DXN的最佳给药途径,以增强患者在ITM手术后的恢复.
主要方法:
- 一项受控,随机的观察性研究,涉及45名接受II类位置B ITM提取的患者.
- 建立了三组:IV-DXN (DXN在IANB之前1小时内静脉注射),PN-DXN (DXN与IANB一起注射),以及对照组 (IANB与盐水).
- 主要结局是麻醉的持续时间;次要结局包括在1日,3日和7日使用视觉模拟尺度评估的术后疼痛和.
主要成果:
- 与对照组相比,静脉注射 (IV) 德克萨米他 (DXN) 显著延长了麻醉时间 (p=0.049).
- 在第3天和第7天,IV和周围神经 (PN) DXN都减少了术后 (分别为p=0.048和p=0.01).
- 术后疼痛在IV-DXN组显著减少 (p=0.011),而PN-DXN组在3日和7日与对照组和IV组相比没有显著的疼痛减轻.
结论:
- 静脉注射 (IV) 和周围神经 (PN) 甲松 (DXN) 两种药物都有效地延长了麻醉的持续时间,并在受冲击的第三 (ITM) 手术中减少了术后.
- 与IV DXN和对照组相比,围膜 (PN) DXN的使用与术后疼痛的增加有关.
- 需要进一步的研究,以探索最佳的DXN剂量和给药途径,以管理在ITM手术中的术后不适.
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