在线接受和承诺干预对血液细胞移植后癌症患者的意义制造过程的影响:随机对照试验的研究协议,增强了单个病例实验设计
Aleksandra Kroemeke1, Joanna Dudek2, Marta Kijowska3
1Institute of Psychology, Health & Coping Research Group, SWPS University, Warsaw, Poland. akroemeke@swps.edu.pl.
Trials
|June 18, 2024
概括
血造细胞移植 (HCT) 患者可能会经历痛苦. 接受和承诺疗法 (ACT) 可以提高心理灵活性,并通过加强在HCT恢复期间的意义创造过程来减少痛苦.
科学领域:
- 在瘤学瘤学.
- 心理学 心理学 心理学
- 移植医学 移植医学
背景情况:
- 血造细胞移植 (HCT) 是一种关键但具有挑战性的血液瘤和癌症的治疗方法.
- HCT可能会破坏患者的意义感,需要进行干预以帮助心理调整.
- 接受和承诺疗法 (ACT) 显示了加强心理灵活性和恢复意义的潜力.
研究的目的:
- 调查在线ACT干预在改善HCT患者的意义创造过程中的有效性.
- 将ACT干预结果与最小增强的常规护理 (mEUC) 控制组进行比较.
- 探索ACT干预对接受HCT的患者的影响背后的变化机制.
主要方法:
- 一个双臂并行随机受控试验,涉及192名患者,他们接受了第一个自身或异构的HCT.
- 参与者可以接受14天的在线自助ACT培训或教育课程.
- 评估包括每日调查和干预建议,在多个时间点进行双盲评估.
主要成果:
- 主要结果是减少与意义相关的痛苦.
- 二次结果包括改善心理灵活性,有意义的应对能力,幸福感和全球/情境意义.
- 一个单个案例实验设计 (SCED) 将为个人提供对干预有效性的独特见解.
结论:
- 这项研究开创了ACT和创造意义的框架的整合,以解决HCT接受者存在的痛苦.
- 这些发现旨在减少与意义相关的痛苦,并提高这一患者群体的整体幸福感.
- 基于网络的ACT自助计划可以解决HCT患者对支持性干预措施的有限访问问题.
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