在神经重症监护人群中使用机械通风的性别差异:一项回顾性研究
Federica Stretti1, Didar Utebay1, Stefan Yu Bögli1,2
1Institute of Intensive Care Medicine, University Hospital Zurich, Rämistrasse 100, Zürich, 8091, Switzerland.
BMC pulmonary medicine
|June 18, 2024
概括
侵入性机械通风 (IMV) 使用中的性别差异在神经临床护理单位 (NCCU) 中没有观察到. 这与一般的ICU形成鲜明对比,表明护理差异可能是诊断特异性的,而不是性别特异性的.
科学领域:
- 神经学 神经学
- 关键护理医学 关键护理医学
- 医学研究 医学研究
背景情况:
- 一般重症监护室 (ICU) 的女性入侵性机械通风 (IMV) 率低于男性.
- 神经临界护理单位 (NCCU) 管理需要输管治疗的患者,包括呼吸衰竭和神经障碍.
- 在NCCU内调查IMV使用的基于性别的差异对于了解护理差异至关重要.
研究的目的:
- 为了确定IMV使用中是否存在性别差异,在神经关键病房 (NCCU) 设置中.
- 为了比较NCCU中男性和女性之间的IMV,输管,再输管和气管切割的频率和持续时间.
- 探索影响神经病患者呼吸支的潜在的性别特异性因素.
主要方法:
- 对在苏黎世大学医院NCCU (NCCU) 住院的成年患者的回顾性分析 (2018年1月 - 2021年8月).
- 数据收集包括人口统计数据,输管细节,气管切除术,以及来自ICU注册和医疗记录的呼吸支的持续时间.
- 进行了描述性统计和对基线和性别结果特征的比较分析.
主要成果:
- 在IMV的使用和持续时间,输入管的频率,再输入管或气管切割方面,没有发现性别之间的显著差异.
- 与男性 (2天) 相比,女性的氧气支持持续时间较长 (3天),通常与下大脑关节出血 (SAH) 相关.
- 在根据年龄,诊断和疾病严重程度进行调整后,在IMV使用或持续时间方面没有观察到基于性别的差异.
结论:
- 与一般ICU不同,这项NCCU研究在侵入性机械通风,输管或气管切除的频率或持续时间上没有发现性别差异.
- 在女性中观察到的氧气支持持续时间的差异与SAH的更高患病率和特定治疗目标有关.
- 这些发现表明,在重症监护服务中的基于性别的差异可能取决于具体的诊断,而不是仅仅取决于性别.
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