注射器服务计划参与者的未满足需求和减少危害的偏好:因非法阿片类药物和甲基胺的联合使用而存在的差异
Rachel Sun1, Tonazzina H Sauda2, Rachel A Hoopsick3
1Department of Psychology, University of Illinois Urbana-Champaign, 603 East Daniel St., Champaign, IL, 61820, USA.
Harm reduction journal
|June 18, 2024
概括
注射毒品 (PWID) 的人同时使用阿片类药物和甲基胺有显著的未满足需求. 量身定制的减伤策略对于这一群体来说至关重要,以满足他们特定的健康和社会服务需求.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 药物成科学 药物成科学
背景情况:
- 美国阿片类药物流行病的第四波涉及阿片类药物和兴奋剂 (如甲基胺) 的联合使用.
- 这种共同使用,称为"goofballing",增加了包括频繁注射,健康问题和发病率在内的风险.
- 参与共同使用的注射药物使用者 (PWID) 可能有不同的未满足的需求和减少伤害的偏好.
研究的目的:
- 在PWID中确定未满足的基本需求和减少危害的偏好.
- 为了比较PWID与非法阿片类药物和甲基胺联合使用者之间的需求和偏好,以及那些不这样做的人.
主要方法:
- 自我报告的数据来自50名参加注射器服务计划 (SSP) 的参与者.
- 评估基本需求和减少危害的偏好.
- 两变量分析用于比较非法阿片类药物和甲基胺的共同使用者和非共同使用者.
主要成果:
- 最高的整体需求包括交通,获得服务的帮助,治疗阿片类药物使用障碍的药物和就业.
- 所有参与者都对芬太尼试验条,安全消费地点以及减少危害的物资 (注射器,纳洛) 的交付表现出高度兴趣.
- 共同使用者报告说,对食物,医疗保健,物质使用障碍治疗,支持服务和运输的需求更大.
结论:
- 在PWID中存在普遍的未满足需求和对减少危害服务的高需求.
- 非法阿片类药物和甲基胺联合使用的个人似乎有最重要的未满足的需求和扩大危害减轻服务的愿望.
相关概念视频
Opioid Analgesics: Synthetic and Semisynthetic Opioids
275
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
275
Drug Abuse and Addiction: Pharmacological Phenomena
464
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
464
Opioid Analgesics: Morphine and Other Natural Cogeners
231
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
231
Analgesia and Pain Management
575
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
575
Substance Use Disorders Affecting Sleep
164
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
164
Drug Dependence
1.0K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.0K


