卡帕阿片类受体的激活通过在血膜上隔离STAT3来抑制创伤后关节炎

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Haixia Liu1, Renhuan Huang1, Ziang Zhuo1

  • 1Department of Stomatology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.

Cell communication and signaling : CCS
|June 18, 2024
PubMed
概括

卡帕阿片类受体 (KOR) 的激活可通过阻止细胞中STAT3信号传递来缓解骨关节炎疼痛和软骨损伤. 这种机制涉及KOR在血上与STAT3结合,抑制驱动OA进展的免疫反应.

关键词:
卡帕的阿片类受体受体.骨关节炎是一种骨关节炎.在STAT3中,我们可以使用STAT3.这就是TNF-α.

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