从提取到稳定:采用2个实验设计,从Bixa orellana开发营养药品级别的Bixin
Christine L Luna-Finkler1, Aralí da C Gomes2, Francisco C A de Aguiar Júnior2
1Department of Antibiotics, Federal University of Pernambuco, Cidade Universitária, Recife 50670-901, PE, Brazil.
Foods (Basel, Switzerland)
|June 19, 2024
概括
安纳托种子提取物 (bixin) 经过冷干燥和马尔托德克斯特林净化并封装. 发现了高封装效率和溶解度的最佳条件,增强了 bixin.
科学领域:
- 自然产品 化学 化学
- 食品科学与技术 食品科学与技术
- 制药科学 制药科学
背景情况:
- 比克辛是来自安纳托种子 (Bixa orellana L.) 的天然胡卜素,在食品,化品和制药行业中作为天然染料.
- 由于消费者对更健康产品的需求,化学添加剂越来越多地被自然染色剂 (如bixin) 取代.
- 比克辛的提取和稳定对于其工业应用至关重要.
研究的目的:
- 为了从安纳托种子中提取和净化 bixin.
- 使用冷干燥与马尔托德克斯作为封装剂来封装比克辛.
- 优化封装参数,以提高双稳定性和可溶性.
主要方法:
- 比克辛的提取涉及连续用有机溶剂 (,甲醇,乙烯酸,二甲) 洗,然后进行结晶.
- 谱光测量用于在各种有机溶剂中进行比克辛分析.
- 一个2 ^ 2的实验设计研究了冷干燥封装的马尔托德克斯特林度 (20-40%) 和比克辛与矩阵的比率 (1:20-1:40).
主要成果:
- 在净化后,获得了1.5 ± 0.2%的比克辛产量.
- 高封装效率 (EE%) 的最佳条件是40%的马尔托德素和1:20的比克辛/马尔托德素比率.
- 封装巴克辛的溶解度较高,观察到20%的马尔托德克斯和1:20的比率.
结论:
- 使用马尔托德克斯特林冷干燥封装比克辛是一种有效的方法来提高其稳定性.
- 该研究确定了高封装效率和溶解度的最佳条件,这对于制药和食品应用至关重要.
- 这种方法为在各种工业产品中使用bixin提供了一个有希望的策略.
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