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Updated: Jun 23, 2025

Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium
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Published on: September 1, 2015

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肌肉相关的转录因子在多囊性病中调解上皮纤维化

Zsuzsanna Lichner1, Mei Ding1, Tarang Khare1,2

  • 1Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, ON M5B 1T8, Canada.

Cells
|June 19, 2024
PubMed
概括

多囊病 (PKD) 涉及囊形成和纤维化. 失去了多素1/2激活了RhoA/细胞骨/肌肉相关转录因子 (MRTF) 途径,导致PKD中的上皮纤维化.

关键词:
由表皮开始的纤维化.与肌肉激素相关的转录因子.益菌性上皮表皮表型的表型∙多囊性脏疾病

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