在整个蛋产卵阶段,肠道基因表达和微生物群的动态变化
Kai Shi1, Xiangping Liu1, Ying Duan1
1College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Animals : an open access journal from MDPI
|June 19, 2024
概括
的肠道微生物和宿主基因表达在产卵期间动态变化. 特定的微生物变化与宿主基因表达相关,共同影响卵产量,并可能改善母的表现.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 基因组学就是基因组学.
背景情况:
- 蛋生产对于家禽养殖至关重要,的表现达到峰值,然后下降.
- 在产卵期间,肠道微生物群的组成发生变化,一些微生物提高了表现.
- 产卵的肠道微生物和宿主基因表达之间的相互作用在很大程度上是未知的.
研究的目的:
- 调查肠道微生物群和宿主基因表达在不同产卵阶段的动态变化.
- 了解肠道微生物与宿主基因表达之间与卵子生产有关的相互作用.
主要方法:
- 在产卵前,产卵高峰和产卵晚期期间,对十二指肠,十足肠和腹的微生物群体和元基因组功能进行分析.
- 转录组分析以确定宿主基因表达变化.
- 特定微生物丰度与宿主基因表达之间的相关性分析.
主要成果:
- 在产卵阶段观察到肠道微生物群落的显著变化.
- 甲基因组分析显示,老年的肠道微生物群中生物合成途径减少和与激素相关的途径增加.
- 转录组分析显示,上调的运输基因,下调的肠发育基因和与产卵率相关的应激反应基因.
- 特定的细菌,包括Lactobacillus,Muricomes和Campylobacter,在不同的肠道部分与宿主基因表达有相关性.
结论:
- 肠道微生物群的组成和宿主基因表达在产卵周期中经历了显著的动态变化.
- 这些微生物和宿主遗传变化与生理变化和产卵性能有关.
- 这些发现表明肠道微生物群和宿主基因表达对蛋生产的联合影响,为改善提供了潜在的目标.
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