运输对血液指数,氧化应激,乳液发酵参数和羊乳液微生物群的影响
Rui Li1, Lizhi Wang1, Binlong Chen2
1Animal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Animals : an open access journal from MDPI
|June 19, 2024
概括
20小时的连续运输对山羊的健康有很大影响,导致严重的压力,免疫功能下降,以及改变了小发酵. 的微生物结构没有受到运输压力的影响.
科学领域:
- 动物科学动物科学
- 兽医医学 兽医医学 兽医医学
- 生理学 生理学 生理学
背景情况:
- 运输是畜牧管理中的常见做法.
- 了解运输压力对山羊的生理和生化影响对于动物福利和生产力至关重要.
研究的目的:
- 调查长时间运输对山羊生理,生化和膜参数的综合影响.
- 评估运输压力对山羊免疫功能,炎症和抗氧化能力的影响.
- 为了评估经过运输后的皮发酵和微生物结构的变化.
主要方法:
- 16只健康的山羊在35-45公里/小时的速度下运输了20个小时.
- 在运输前和运输后测量了生理学,血液,生物化学和肠发酵指数.
- 使用多样性指标和相对丰富度在类和属层面分析了体微生物结构组成.
主要成果:
- 运输显著降低了免疫球蛋白M (IgM),免疫球蛋白A (IgA),免疫球蛋白G (IgG) 和甲状腺素水平.
- 在酸,血红蛋白,上腺素,挥发性脂肪酸 (VFA) 和炎症标志物 (LPS,IL-1β,IL-6,TNF-α) 中观察到显著增加.
- 检测到没有显著的变化,在肠微生物的α-多样性,β-多样性,或相对丰度在科或属的水平.
结论:
- 20小时的运输会引起山羊的严重应激反应,损害免疫功能和抗氧化能力.
- 运输对炎症状况产生重大影响,并改变了小麦芽发酵模式.
- 体微生物群的结构和组成在很大程度上不受这种运输压力的持续时间的影响.
相关概念视频
Assessment of Diffusion and Perfusion
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
Oxygen Transport in the Blood
Hemoglobin (Hb) is a crucial molecule in the human body, consisting of four polypeptide chains, each bound to an iron-containing heme group. This unique structure enables hemoglobin to bind to oxygen, with each molecule capable of combining with four molecules of oxygen, leading to rapid and reversible oxygen loading. When fully loaded with oxygen, it is called oxyhemoglobin, while hemoglobin that has released oxygen is called reduced hemoglobin or deoxyhemoglobin. As hemoglobin binds oxygen,...
Bioreactor Design and Operational System
Bioreactors are engineered vessels designed to cultivate microorganisms under controlled conditions for industrial bioprocessing. They maintain sterility and allow precise regulation of pH, temperature, oxygen, and nutrient levels to optimize microbial growth and metabolite production. Bioreactors range from small laboratory units of 1 liter to industrial systems holding up to 500,000 liters, though only about 75% of their volume is actively used for fermentation. The remaining headspace...
Bioreactor Controls-I
Maintaining optimal conditions within fermenters is essential for maximizing microbial productivity and ensuring process efficiency. This lesson focuses on key parameters—temperature, foam, pH, carbon dioxide, oxygen, and pressure—and their precise measurement and control strategies in fermentation systems.Temperature ControlTemperature regulation is critical due to the exothermic nature of many fermentation processes. In small laboratory fermenters, temperature is commonly monitored using...
Bioreactor Controls-II
In aerobic fermentations, oxygen is vital for microbial growth and metabolite production. Since air comprises only about 20% oxygen and the gas is poorly soluble in water—just 9 ppm at 20°C—supplying sufficient oxygen becomes a critical challenge, especially in high-demand processes like yeast growth or citric acid production. Even a fully saturated broth may offer only a few seconds of oxygen availability.To address this, sterile or scrubbed air is introduced into the fermentor via a sparger...
Designing Growth Media for Bioreactors
Growth media provide essential nutrients that support cell growth and metabolism, thereby enhancing the yield of valuable products such as enzymes, antibiotics, and biomass. Designing an effective growth medium involves balancing all components to prevent nutrient limitations or toxic excesses, both of which can impair growth and reduce product yields.Composition of a Typical Growth MediumA typical growth medium contains carbon and nitrogen sources, salts, vitamins, trace elements, and...


