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Updated: Jun 23, 2025

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
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RANKL,但不是R-Spondins,通过LGR4相互作用参与血管光滑肌肉细胞化

Sara Fernández-Villabrille1,2, Julia Martín-Vírgala1,2, Beatriz Martín-Carro1,2

  • 1Metabolismo Óseo, Vascular y Enfermedades Inflamatorias Crónicas, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), 33011 Oviedo, Spain.

International journal of molecular sciences
|June 19, 2024
PubMed
概括

血管化与骨质损失有关. 这项研究揭示了核因子卡帕B连接体 (RANKL) 的受体激活剂与含有丰富的白素的重复含有G蛋白结合受体4 (LGR4) 相互作用,通过促进光滑肌肉细胞中的骨质分化,驱动血管化.

关键词:
在LGR4LGR4它们是R-spondins.兰克尔 (Rankl) 是一个名字.是一种的物质.血管化 血管化

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