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Updated: Jun 23, 2025

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
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对结直肠癌的遗传洞察:评估PI3K/AKT信号通路的基因表达

Rafał Świechowski1,2, Jacek Pietrzak1,2, Agnieszka Wosiak1,2

  • 1Department of Pharmaceutical Biochemistry and Molecular Diagnostics, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland.

International journal of molecular sciences
|June 19, 2024
PubMed
概括

这项研究表明,PI3K/AKT通路基因表达,特别是FOXO1,在结直肠癌中随年龄和瘤位置而变化. PTEN和FRAP基因表达水平与患者的结果相关,为癌症进展提供了洞察力.

关键词:
一个AKT1一个AKT1通过PI3K/AKT路径.这就是PIK3CA.结肠直肠癌是什么意思基因表达的基因表达方式

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